salicylic acid

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50g

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Pharmaceuticals: Active ingredient in topical treatments for acne, psoriasis, seborrheic dermatitis, warts, and corns/calluses.
Cosmetics & Personal Care: Key ingredient in cleansers, toners, masks, and spot treatments for its exfoliating and pore-clearing benefits. Concentration limits are strictly regulated.
Food Preservative: Used in very low concentrations (regulated) to inhibit mold and bacteria.
Industrial: As a starting material for the synthesis of aspirin (acetylsalicylic acid) and other chemicals.

This table outlines the standard specifications for high-purity Salicylic Acid.

PropertySpecification / DescriptionTest Method (Typical)
Appearance	White or almost white, crystalline powder or fine needles.	Visual Inspection
Odor	Odorless or with a faint, characteristic odor.	-
Assay (Purity)	Not less than 99.0% and not more than 101.0% (on dried basis).	Titration (Acid-Base) or HPLC
Melting Point	158°C - 161°C	USP <741> / Ph. Eur. 2.2.14
Loss on Drying	Not more than 0.5% (1g, over silica gel for 5 hours).	USP <731> / Ph. Eur. 2.2.32
Sulfated Ash / Residue on Ignition	Not more than 0.1%	USP <281> / Ph. Eur. 2.4.14
Heavy Metals	Not more than 20 ppm	USP <231> / ICP-MS
Related Substances	Total impurities: Not more than 0.5%	Any individual impurity: Not more than 0.1%	HPLC
Solubility	Sparingly soluble in cold water.	Freely soluble in ethanol (alcohol), ether, and boiling water.	-
pH (Saturated Solution)	Approximately 2.4 (highly acidic)	Potentiometric

Positive identification tests are required to confirm the material.

A. Iron (III) Chloride Test: A dilute aqueous solution gives a violet color upon the addition of ferric chloride solution.
B. Melting Point: The melting range should conform to the specification (158°C - 161°C).
C. Infrared Spectroscopy (IR): The IR absorption spectrum of the sample should correspond to that of a reference standard.